Cannabidiol or CBD has recently been known for offering many health benefits. It can fight anxiety, stress, reduce inflammation, protect your body from neurodegenerative diseases, reduce pain, cure nausea, reduce seizures, etc. The role of CBD in curing seizures has received lots of media attention.
Epilepsy is a disorder in which nerve cell activity in the brain is disturbed, causing seizures.
There are about 40 types of epilepsy, some of which are treatable by medication or changes in diet and lifestyle. Some which cannot be treated include Dravet syndrome and Lennox-Gastaut syndrome. CBD can cure Dravet as well as Lennox-Gastaut syndrome.
The study centered around 120 individuals between the ages of 2 and 18. All of them had been diagnosed with Dravet syndrome or other seizures that have proven to be drug-resistant. The study was unique to most other CBD studies in that it was both a placebo-control trial as well as a double-blind study. This is considered the gold standard when it comes to medical studies.
The researchers had patients and their caregivers supervise epileptic activity, first during a baseline period of 4 weeks and then over a 14 week period, during which the treatment was given. The treatment was either an oral does of cannabidiol or the placebo. The dose was based on body weight and given to the patient each day. During the 18 week period, other treatments that participants were using to control their seizures were not to be disrupted.
When the results were compiled, researchers found that under the placebo, participants saw a slight decrease in convulsive seizures. Instead of 14.9 seizures per month, they had 14.1. The participants who took the daily CBD oil for seizures saw a much more dramatic difference. Before the CBD, the participants had an average of 12.4 seizures per month. During the study, this number dropped to 5.9 per month. When this is broken down, 27% of the placebo participants saw their monthly seizure average drop by half, compared to 43% of the CBD participants. The Caregiver Global Impression of Change scale was also used to show improvement with the study’s participants. With 34% of the placebo group, particpants saw an improvement by at least one category on the scale over the course of the study. Among the participants receiving CBD, 62% saw improvement by at least one category. Finally, the most shocking result occurred for 5% of the participants who were receiving CBD oil for seizures. They became seizure-free over the course of the trial. This did not occur in the any of the participants who were taking the placebo.
Hence, the results proved that CBD had a positive effect on the patients for controlling seizures. The participants of the trial were taking their regular medication along with CBD. Whether CBD increased the efficacy of the medication, or actually reduced the seizures is still left to be discovered.
Cannabis contains properties that are anti-convulsant. Hence, it has the ability to control seizures in the brain.
As cannabidiol is widely used across the US, researchers have started creating studies to aloe perfect CBD dosing and identify how it is better than anti-epileptic medication. This will introduce more drugs like Epidiolex, to cure epileptic seizures.