Scientists pinpoint CBD dose for safe pain and anxiety relief
Cannabis is known to have one of the prominent chemical compounds called cannabidiol (CBD), which has the potential to reduce pain and anxiety in users. The most attractive fact why people are inclined towards using CBD extract is because of its medicinal properties that come along without the high. Cannabis is usually associated with producing a psychotic effect in the user, but the latest study has revealed effective dose of CBD is completely safe and excellently offers relief from the pain.
Cannabis consists of more than 100 chemical compounds known as cannabinoids that has potential to impact particularly on receptors in cells while altering the neurotransmitter release in the brain. THC another famous cannabinoid is entirely responsible for generating a psychoactive effect on the user. While looking at the molecular structure closely, both CBD and THC have a similar structure, i.e. 30 hydrogen atoms, 21 carbon atoms, and 2 oxygen atoms. However, the atoms are arranged in quite a different way in both the chemical compounds which produces both the compounds to react differently in the body. The THC compound stimulates the CB1 receptor while altering the senses. This was until discovered that CBD also stimulated CB1, without altering the senses.
The researchers of the McGill University, Canada and the Institute of the McGill University Health Centre (MUHC) were keen on finding the dosage of the CBD where it is effective. In the research, they found that CBD doesn’t exactly act on CB1 cannabinoid receptors as THC does. But, the mechanism has the ability to bind specific receptors that are involved in reducing pain (vanilloid TRPV1) and anxiety (serotonin 5-HT1A).
The researchers also found that those rats that were given an intravenous dose of 5 mg/kg/day of CBD improved 5-HT firing through desensitization of 5-HT1A receptors. Treating them with CBD for a week helped in reducing the painful symptoms while experiencing no signs of pain, and a dramatic reduction in anxiety as well. Administering low doses of the CBD for 7 days in animal models showed an acute reduction in chronic pain and anxiety.
These findings are considered essential in the field of medical marijuana or CBD. Moreover, the extract has become quite popular that one can easily find CBD oil or CBD infused products everywhere in the USA. Even the CBD market is growing at a great pace.